In the 1970s, in the Peruvian Amazon forest, scientist Constance Webb searches for a legendary spider. As soon as she finds it, however, she is betrayed by Ezekiel Sims, who shoots her and steals the spider for himself. Constance cannot be saved even by the AraƱas, a tribe endowed with mystical spider powers, who however will give birth to her daughter Cassandra. Thirty years later, in New York, Cassandra is an affectionless paramedic whose life is turned upside down when, following an accident, she develops the power to see into the future...
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